TriLegest Fe Birth Control Pills

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Equivalent Generic Brands: Estrostep Fe

5.0 - 2126 Reviews

$46 generic equivalent, $0 with most insurance

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What is TriLegest Fe Birth Control Pills?

TriLegest Fe is a combination oral contraceptive pill (OCP, birth control medication, birth control pills) that consists of combination norethindrone and ethinyl estradiol tablets. This hormonal birth control works to prevent pregnancy by thickening the cervical mucus which blocks the sperm from getting into the uterus and creating a fertilized egg and by thinning the uterine lining (endometrium) such that if the egg/sperm hook up, there’s nowhere to stick and grow. Read More

How to Use TriLegest Fe

It’s very easy to use!

Simply take one pill every day, at the same time each day. Many women find that taking TriLegest Fe before bedtime or with your largest meal of the day helps reduce nausea and other side effects.

After taking 21 days of the white active medication pills, you’ll switch to 7 green inactive pills that contain ferrous fumarate. These are inactive pills (placebo) work as reminder pills with no hormones that are there to get you in the habit of taking your pill every day.
If you do miss one active pill , take two pills as soon as you remember. Then, continue to take one active pill for the rest of the pill pack. If you miss two active pills in a row take two pills per day for two days. However, if you miss three active pills in a row, do not take the missed pills. Instead you should use a back up birth control method for at least 7 days. Note that you may experience some bleeding or spotting if you miss three pills in a row. Continuously missing doses could lead to oral contraceptive failure.

Remember that TriLegest Fe cannot be used to prevent HIV infection or other sexually transmitted diseases. In order to prevent STDs, always use condoms when having sexual intercourse.

TriLegest Fe Dosage

TriLegest Fe has two main active ingredients: Norethindrone Acetate 1mg (progesterone) and Ethinyl Estradiol 20/30/35 ug (estrogen).

Benefits of TriLegest Fe

TriLegest Fe Side Effects

Most people who take TriLegest Fe experience no side effects. If side effects occur, they are usually mild.

Some minor side effects are: headaches, nausea, breast tenderness, breakthrough bleeding, fatigue, and decreased sex drive. TriLegest Fe is not recommended for women who are breastfeeding, as it may slow breast milk production. Many experience positive side effects such as: reduced acne, fewer mood swings, and lighter, easier, and less painful periods!

While very unlikely, serious side effects can occur while taking TriLegest Fe, including blood clots. Blood clots can travel throughout the bloodstream and block blood flow to different parts of the body. This can cause potentially life-threatening issues like deep vein thrombosis, heart attack, or stroke. If you experience other serious side effects such as sudden heavy bleeding, liver problems (dark urine, jaundice) please call a health care professional.

Additional side effects include blotchy skin (melasma) which can be worsened by sunlight, tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Those who wear contact lenses or are nearsighted may notice vision problems as well.

The good news is that the risk of serious TriLegest Fe side effects is extremely low. Our expert birth control doctors and Pandia Health Care Advisors can answer any questions and concerns about your birth control options.

TriLegest Fe Warnings

    Do NOT take this medication if:

  • You currently have or have had any of these health problems: blood clots, blood clotting problem, breast cancer, uterine cancer, heart attack, stroke, heart disease, chest pain, high blood pressure, liver disease, liver tumor, migraine with aura, or diabetes with neuropathy or any diabetic complications
  • You are allergic to ethinyl estradiol
  • You are taking ombitasvir, paritaprevir, and ritonavir
  • (with or without dasabuvir)
  • You are pregnant or may be pregnant
  • You are breastfeeding or plan to breastfeed

Why Pandia Health?

FREE with insurance, $33/Pack without

FREE with insurance, $33/Pack without

FREE Delivery & Goodies

FREE Delivery & Goodies

Online prescription (skip the Dr. office visit and pharmacy lines)

Online prescription (skip the Dr. office visit and pharmacy lines)

Frequently Asked Questions


There is no direct link between TriLegest Fe and weight gain. Some women experience changes in their appetite that may lead to weight gain while taking TriLegest Fe. Others may find that their bodies experience more fluid retention while taking TriLegest Fe, even though they actually don’t gain any body fat.


One of our Patient Care Advisors or licensed physicians will always review the medications and supplements you’re currently taking before prescribing TriLegest Fe. Certain drugs (herbal supplements, recreational, over-the-counter, prescription, or any other drugs) can have possible drug interactions with TriLegest Fe and make it less effective by decreasing the amount of birth control hormones in your body. Drugs that may interact with oral contraceptives like TriLegest Fe include HIV drugs, anti-seizure drugs, antibiotics, and even herbal supplements like St. John’s wort.


You shouldn’t smoke anyway, but especially not if you take estrogen containing birth control pills like TriLegest Fe. Smoking increases the risk of serious side effects like blood clots, especially in women who are older than 35.

Don’t take TriLegest Fe if you’re allergic to any of its ingredients. Signs and symptoms of an allergic reaction to TriLegest Fe are rare and usually very mild and may include itching, hives, or dizziness. Serious allergic reactions to TriLegest Fe can occur in very rare cases. Stop taking TriLegest Fe and call 911 immediately if you experience swelling in the lips, mouth, or tongue, or if you have a hard time breathing.

TriLegest Fe isn’t for everyone. Women with a history of certain medical conditions like heart disease, high blood pressure, kidney disease, liver cancer, gallbladder disease, breast cancer, or severe migraines should not take TriLegest Fe. Our Pandia Health Care Advisors are standing by to help you figure out the best birth control method given your health history.


It’s easy to get TriLegest Fe at just about any pharmacy near you with a doctor’s prescription. Concerned about your privacy? Our doctor-founded, doctor-led team at Pandia Health is happy to connect you with a licensed physician who can help you get TriLegest Fe or any other birth control you need, discreetly and conveniently.

If you don’t have insurance, don’t worry! Pandia Health has a range of payment options.


It’s not true that TriLegest Fe causes infertility. If you’re taking TriLegest Fe and want to have a baby, talk to your doctor and then stop taking the medication. Normal fertility should return within one or two menstrual cycles after your last pill. Dr. Yen explains more about birth control and infertility in this video. Watch to learn more!

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