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Equivalent Generic Brands: Progesterone


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Prometrium Benefits

Regulation of the menstrual cycle. Prometrium is made with progesterone, a hormone that helps regulate the menstrual cycle. It can help restore normal periods in women who have irregular or absent menstrual cycles.

Reduction of the risk of endometrial hyperplasia

Alleviation of menopausal symptoms

Improved bone health

Product Details

How to use Prometrium

As part of a menopausal hormone therapy, a woman with uterus who is taking estrogens should take a single daily dose of 200 mg Prometrium Capsules at bedtime for 12-14 continuous days during a 28-day cycle. It is important to follow the recommended usage instructions for Prometrium to achieve the best results. Take the capsule orally, with or without food, as directed by your healthcare provider. It is generally advised to take Prometrium at bedtime to minimize potential side effects like dizziness or drowsiness and to contribute to better sleep. Stick to a consistent schedule and take the medication at the same time every day for maximum effectiveness.

If you miss a dose, take it as soon as possible. If it’s almost time for the next dose, only take that dose. Taking two doses at the same time is not recommended.

Prometrium Side Effects

While Prometrium is generally well-tolerated, some individuals may experience mild side effects. These can include:

  • Dizziness
  • Headache
  • Breast tenderness
  • Mood swings
  • Nausea
  • Bloating or water retention
  • Changes in appetite

Serious side effects are rare but can include an increased risk of blood clots, stroke, heart attack, and certain types of cancer. Contact your doctor immediately if you experience:

  • Chest pain with or without shortness of breath, weakness or fatigue
  • Severe headache
  • Changes in vision or speech
  • Signs of an allergic reaction (swelling of the face, tongue, mouth or throat)

If you experience any of the above warning signs of a serious side effect, contact your healthcare provider immediately. We encourage you to contact your healthcare provider to share any concerning symptoms you may experience when the treatment is started.

Note: this is not a full list of Prometrium possible side effects, if you note any side effect that is not listed contact your doctor or pharmacist to get the right advice.

Prometrium Contraindications

You should not use Prometrium if you have any of the following conditions on your health history:

  • Allergic to Progesterone or any ingredients in the medication.
  • Allergic to peanuts.
  • Have abnormal vaginal bleeding that has not been checked by a doctor.
  • Have history of blood clots: Women with a history of blood clots in the legs (deep vein thrombosis) or lungs (pulmonary embolism) should avoid using Prometrium since it can increase the risk of blood clot formation, which can be life-threatening.
  • Have a history of heart attack or stroke: Women with a history of heart attack or stroke should generally avoid using Prometrium. The medication can increase the risk of cardiovascular events in individuals with a history of these conditions.
  • Breast cancer: Women with a history of breast cancer or other hormone-sensitive cancers should generally avoid using Prometrium. It can potentially stimulate the growth of hormone-sensitive tumors.
  • Liver disease: Severe liver disease or liver tumors are contraindications for the use of Prometrium.
  • Pregnancy: Prometrium may cause harm to the development of the fetus.

These contraindications are general guidelines, and individual patient factors and medical history should be considered when determining the appropriateness of using the Prometrium as part of menopausal hormone therapy. If a doctor prescribed this medication as part of your menopause treatment, your individual factors and health history should have been evaluated making sure that the medication will not put your health at risk.

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What is Prometrium?

Prometrium is a widely recognized medication that offers effective relief for certain menopause symptoms. This prescription medication is progesterone, a natural hormone that helps regulate the menstrual cycle and supports a healthy reproductive system.

During the menopause transition progesterone and estrogen levels start to fall, leading to hot flashes, mood swings, lack of sleep and other known menopausal symptoms. If your body is no longer producing enough progesterone your doctor may prescribe Prometrium as part of a Menopausal Hormone Therapy.

This medication is used in combination with estrogen-containing medications in postmenopausal women who have a uterus (womb). Taking estrogen alone increases the risk of developing a condition called endometrial hyperplasia, which may lead to uterine (womb) cancer. So adding a progestin is generally advised for women with a uterus to reduce the chance of developing uterine cancer.

Prometrium can be also prescribed for managing secondary amenorrhea (absence of menstrual periods in women who have previously had a menstrual period) caused by low levels of progesterone. Insufficient progesterone production can lead to menstrual irregularities. If your healthcare provider determines that your body doesn’t produce enough progesterone naturally, Prometrium may be recommended to supplement the required progesterone.

Frequently Asked Questions

Yes, Prometrium is a bioidentical/body-identical form of progesterone. It is a brand name for the hormone progesterone that is chemically identical to the progesterone naturally produced by the body.

Prometrium is a medication that contains the hormone progesterone. It is primarily used in women who have a deficiency of progesterone and/or to offset the administration of estrogen in MHT. Prometrium is commonly prescribed to treat various conditions such as irregular menstrual periods, amenorrhea (absence of periods), endometriosis. It may also be used as part of hormone replacement therapy in menopausal women.

Yes, Prometrium is the same as progesterone. Prometrium is a brand name for a specific form of progesterone called micronized progesterone. Progesterone is a hormone naturally produced by the ovaries in women and is involved in regulating the menstrual cycle and preparing the uterus for pregnancy. Prometrium is often prescribed as a medication to supplement progesterone levels in women who have low progesterone, are taking estrogen in MHT or have hormonal imbalances.

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