Benzaclin Gel

5.0 - 2177 Reviews

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$43 generic equivalent, $0 with most insurance

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Benzaclin Gel Benefits

Reduces the number of pimples and improves the overall appearance of the skin.

Kills bacteria and reduces inflammation, targeting two of the main causes of acne.

Reduces the number of pimples and improves the overall appearance of the skin.

Easy to apply directly to the affected areas of the skin.

Well-tolerated and side effects are usually mild and temporary.

Product Details

How to use

Gently wash the area affected by acne with warm water and mild soap. Pat dry and with clean hands, apply a thin layer of gel , rubbing it into the skin gently. Repeat the process once or twice daily, as directed by your doctor.
Avoid getting the medication in your eyes, nose, or mouth. If you experience any irritation or dryness, you may want to apply a moisturizer after the medication has dried.

It is important to use Benzaclin regularly and as directed to see the best results. It may take several weeks to see improvement in your acne. If you have any questions about how to use Benzaclin, talk to your doctor or sign up to get one of our expert doctor’s advice.


Benzaclin mixes 10mg clindamycin and 50mg benzoyl peroxide per gram of gel. It’s a gel with Clindamycin 1% and Benzoyl peroxide 5%.

Side Effects

Benzaclin like any medication may cause side effects in some people. Some common side effects of Benzaclin include dryness, itching, redness, burning, or peeling of the skin where the medication is applied.
Other possible side effects include skin discoloration (can get lighter or darker) and abdominal pain. In rare cases, Benzaclin can cause severe allergic reactions, such as difficulty breathing, swelling of the face, lips, tongue, or throat, hives, or blistering of the skin. If you experience any of those symptoms, seek medical attention immediately. These symptoms may or may not be accompanied by fever. Difficulty in breathing, talking, or swallowing, tightness in the chest or throat, wheezing, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat are also allergic reactions to look for. If you experience any of them, call 911 immediately or go to the nearest emergency room.

Some cases of severe colitis have been reported during the treatment or weeks-month after finishing. If you experience severe persistent diarrhea or severe abdominal cramps reach out to your doctor or for medical care as soon as possible and mention you are or were taking Benzaclin. Do not take other medications to stop the diarrhea until a doctor advises you to do so because they can cause the symptoms to worsen.


Some warnings to consider before using Benzaclin are:

  • Benzaclin should not be used by individuals who are allergic to benzoyl peroxide, clindamycin, or any other ingredient in the medication.
  • Benzaclin may cause skin irritation, especially during the first few weeks of treatment. If irritation persists or becomes severe, discontinue use and consult your doctor.
  • Avoid getting Benzaclin in your eyes, nose, mouth, or on your lips. If this happens, rinse the affected area with water and seek medical attention if necessary.
  • Benzoyl peroxide may bleach hair and clothing. Be careful when applying Benzaclin to avoid contact with clothing or hair. The benzoyl peroxide may bleach your pillow cases, towels, t-shirts, clothing.
  • Benzaclin may make your skin more sensitive to sunlight. Avoid sun exposure and tanning booths or tanning beds. Use sunscreen and wear protective clothing when outdoors.
  • Benzaclin may interact with certain medications, such as erythromycin, which may increase the risk of colitis. Consult with your doctor about potential interactions before using Benzaclin.
  • It is important to use Benzaclin as prescribed, do not use more or less than recommended by your doctor.
  • Benzaclin is contraindicated in those having a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis
  • There is not enough significant scientific data about Benzaclin used by pregnant women. Benzaclin is Pregnancy Category C = it is not known whether or not Benzaclin would harm a growing fetus. Benzaclin topical gel is probably fine during breastfeeding because it is topical and not shown to pass into the breast milk. Consult your doctor before starting to use any other herbal medications or other drugs. They may interact with the medication.


Please, note these are only some interactions. Always let your doctor know before starting any new medication and or supplement (vitamins, dietary supplements or herbal supplements).

Interactions with other medications:

  • Benzaclin may interact with certain medications, such as erythromycin. Combining these medications may increase the risk of antibiotic resistance or reduce the effectiveness of both treatments. It is important to consult with your healthcare provider before using Benzaclin if you are taking any oral medications for acne or other skin conditions.
  • Benzaclin should not be used in combination with other topical medications that contain erythromycin or clindamycin. Combining these medications may increase the risk of skin irritation or adverse reactions.
  • Other medications that should be avoided while using Benzaclin are: Atracurium, Metocurine, and Tubocoranine. The use of these medications combined with Benzaclin can increase the risk of some side effects.
  • Interactions with cosmetic products

  • It is generally safe to use Benzaclin with cosmetic products, but it is recommended to apply any cosmetics after the medication has fully dried on the skin. This helps to minimize the potential for interaction or interference with the medication’s effectiveness.
  • Interactions with diseases:

  • Colitis
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Benzaclin is a prescription medication that’s used on the skin to treat acne (inflammatory acne vulgaris). This topical acne medication combines benzoyl peroxide and clindamycin. Benzoyl Peroxide kills the bacteria and helps slough off dead skin cells while Clindamycin stops the growth of bacteria that causes acne, decreasing inflammation. Both components work together to reduce the amount of bacteria on the skin and decrease inflammation.
Benzaclin is only available with a prescription. Pandia Health’s expert doctors are happy to help you get the right skin treatment for you.

Frequently Asked Questions

Benzaclin gel is used to treat acne vulgaris, a common skin condition characterized by the formation of pimples, blackheads, and whiteheads on the forehead, jawline, chin, cheeks, neck, chest, and back. It contains a combination of two active ingredients, benzoyl peroxide and clindamycin, which work together to reduce inflammation, kill bacteria that cause acne, and prevent new breakouts from forming. Benzaclin gel is applied topically to the affected area once or twice daily as directed by your doctor. It is important to use Benzaclin as prescribed and to follow your doctor’s instructions carefully to achieve the best results.

No, Benzaclin is a prescription medication that cannot be purchased over the counter. It contains a combination of benzoyl peroxide and clindamycin, which are both powerful medications used to treat acne. To obtain Benzaclin, you will need a valid prescription from a licensed doctor. At Pandia Health we have expert doctors on acne medications who can prescribe generic Benzaclin if that fits your needs. If Benzaclin is not your best fit, our doctors will suggest other acne medications to help you get clear skin. Our doctors can find the best acne treatment for you and we offer FREE delivery! Sign up today to say bye to acne!

The amount of Benzaclin that you should apply depends on your doctor’s instructions and the severity of your acne. Typically, a pea-sized amount of gel is enough to cover the entire face. You should apply Benzaclin to clean, dry skin once or twice daily or as directed by your doctor. It is important not to use more than prescribed, because doing that may increase the risk of side effects such as skin irritation and dryness. 

Benzaclin should be left in the affected area. There’s no need to wash it off. It is important not to wash or rinse the treated area immediately after applying Benzaclin, because doing so may reduce its effectiveness. If you experience skin irritation or discomfort while using Benzaclin, consult with your doctor for advice on how to best use the medication.

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