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Combined Oral Contraceptive Pill (cOCP)


Treats Acne
Regulates Periods
Treats Irregular Periods
Less Painful Periods
Prevents Pregnancy
Decreases Heavy Periods
Decreases Anemia
Decreases Monthly Blood Loss
Decreases Risk of Ovarian Cysts
Decreases Risk of Ovarian Cancer
Decreases Risk of Endometrial Cancer
Decreases Risk of Colorectal Cancer

Active Ingredients

Drosperinone (progesterone) [3 mg]

Ethinyl Estradiol (estrogen) [20 mcg]


Do NOT use if allergic to estrogen or progestin.

Discuss use with doctor before breastfeeding, may decrease milk volume.

Equivalent Generic Brands

Drospirenone/ Ethinyl Estradiol

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New Questions


What is Nikki?

Nikki is a “low dose” combination oral contraceptive pill (OCP, birth control medication, birth control pills) with only 20mcg of ethinyl estradiol (estrogen). Our CEO & Co-Founder Dr. Sophia Yen does not recommend “low dose” pills for those aged 30 and under because it is not good for your bone density. It is better to be on a birth control pill with a minimum of 30 mcg of estrogen (ethinyl estradiol) until you are 30 years old. Watch this video if you want more information. Instead, Dr. Yen recommends you use the slightly higher dose version of this medication = Yasmin and its generics.

Nikki prevents pregnancy by preventing the release of an egg (ovulation), and thickening the cervical mucus, blocking sperm from getting into the uterus and getting to the egg.

Nikki is also prescribed to: treat acne, reduce the risk of ovarian cysts (as in polycystic ovarian syndrome [PCOS]), treat painful or heavy periods and more.

If you have high blood pressure or take blood pressure medications, this medication is NOT for you. Instead, Pandia Heath Medical group’s doctors recommend progestin-only pill (POPs), IUD with hormone (Mirena, Liletta, Kyleena, Skyla), implant (nexplanon), the birth control shot (depo-provera), or condoms and spermicide.Pandia Health’s doctors are always happy to help you choose the right birth control for you. Pandia Health’s doctor team can prescribe Nikki at special request or another generic equivalent: Gianvi, Lo-Zumandimine, Vestura, Drospirenone /Ethinyl estradiol, or Jasmiel for as low as $0 with insurance or as little as $15/pack (3 pack minimum) without insurance.


Will Nikki Cause Weight Gain?

Very few women experience weight gain when taking Nikki. Nikki has a theoretical diuretic effect, meaning it helps shed water from the body.

Any Other Important Information About Nikki?

As with any new prescription, you should go over anything you’re already taking with your doctor or Pandia Health Care Advisor before starting on Nikki. This includes recreational drugs, over-the-counter meds, and even herbal supplements. Even something as relatively harmless as St. John’s wort can cause Nikki to be less effective at preventing pregnancy. There are certain meds you should absolutely bring up. These are aromatase inhibitors, cancer medications, HIV drugs, seizure medicines, and those used for chronic hepatitis C.

Does Nikki Cause Side Effects?

The risks are very low, but some women have experienced unwanted side effects when taking Nikki. Minor ones include breast tenderness, headaches, nausea, swollen feet or ankles, and slightly elevated blood pressure, or blood sugar levels. Positive side effects are also a possibility, too — reduced acne, fewer mood swings, and other perks are fairly common. The chances of serious side effects are extremely unlikely, but some cases have been documented such as blood clotting, shortness of breath, migraines, vision problems, slurred speech, confusion, and fainting. These may sound scary, but remember — they’re very rare.

What Precautions Should I Be Aware of with Nikki?

Pretty much every kind of prescription birth control comes with a tiny risk of allergies, including Nikki. The symptoms are usually mild and include rashes, itching, dizziness,  or more serious symptoms of trouble breathing, and swollen lips, throat, or tongue. If you experience the latter, STOP the medication and call 911 or at least go to the emergency room.

Depending on your medical history, hormone-based birth control may not be for you. It’s important to discuss your medical history with your physician or one of our helpful Pandia Health Patient Care Advisors before you get started on Nikki. This is especially the case if you have cancer, heart disease, blood clotting, diabetes, or high blood pressure.

How Easy Is It to Get Nikki?

Nikki should be available at any pharmacy. It does require a prescription from a doctor/NP/PA, though. If you’re hesitant to approach a doctor/provider about Nikki or simply prefer the privacy, confidentiality, and ease of the internet, give Pandia Health a try.

We have licensed, expert birth control doctors in every state we operate in. We also accept almost all forms of private insurance here at Pandia Health. If you choose to pay out-of-pocket, Nikki is quite affordable because it’s a generic brand. You can also save by choosing one of several other Nikki generics, such as Gianvi, Lo-Zumandimine, Vestura, Drospirenone/ Ethinyl Estradiol, and Jasmiel.

No insurance? No problem. We also offer many payment options to fit your needs.

How Does Nikki Work?

Nikki uses a blend of two hormones, estrogen and progestin, to make your body think it’s pregnant so a real pregnancy won’t happen. It’s super easy to use. Simply take one pill every day, at the same time each day.

Many women find that taking Nikki before bedtime or with your largest meal of the day helps reduce nausea and other side effects. After taking 24 days of active pills, you’ll switch to 4 days of inactive/placebo/sugar pills. These inactive/placebo pills with no hormones are there to keep you in the habit of taking a pill every day.

Does Birth Control Cause Infertility?

Some women worry that birth control pills like Nikki can cause long-term fertility issues. This isn’t true. If you want to have a baby soon, just stop the medication and you should return to full fertility within a cycle or two after stopping.

Watch our video by our Co-Founder and CEO Dr. Yen about birth control and infertility.