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Prempro 0.45mg/1.5mg

5.0 - 2177 Reviews

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$246

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Prempro 0.45mg/1.5mg Benefits

  • Relief of menopausal symptoms: Prempro helps alleviate common symptoms of menopause such as hot flashes, night sweats, vaginal dryness, and mood swings.
  • Prevention of osteoporosis: The estrogen component in Prempro helps maintain bone density, reducing the risk of osteoporosis in postmenopausal women.
  • Regulation of menstrual cycle: Prempro can help regulate irregular menstrual cycles in women experiencing perimenopause.
  • Helps protect your uterus
  • Product Details

    How to use Prempro 0.45mg/1.5mg

    How to use Prempro 0.45mg/1.5mg

    Prempro is very easy to use! Simply take one tablet daily, at the same time each day.

    It is always important to follow the instructions provided by your healthcare provider and not to exceed the recommended dosage. If you miss a dosage, take the medicine as soon as you can, but skip the missed dose. Do not take two doses at one time.

    Prempro 0.45mg/1.5mg Side Effects

    Prempro 0.45mg/1.5mg Side Effects

    While Prempro can provide significant benefits, it may also cause certain side effects. Common side effects may include breast tenderness, headache, nausea, bloating, fluid retention, vaginal bleeding, and mood changes. Contact your healthcare provider if these side effects persist or worsen.

    Serious side effects are rare but can include an increased risk of blood clots, stroke, heart attack, and certain types of cancer. Contact your doctor immediately if you experience:

    • Jaw or shoulder pain, chest pain or pressure, nausea, sweating
    • Slurred speech, sudden numbness or weakness (especially on one side of the body), sudden severe headache, problems with vision or balance
    • Stabbing chest pain, sudden vision loss, feeling short of breath, coughing up blood, pain or warmth in one or both legs
    • Swelling or tenderness in your stomach
    • Yellowing of the skin or eyes (jaundice)
    • Unusual behavior, memory problems, confusion
    • Pelvic pain, unusual vaginal bleeding
    • A lump in your breast
    • Unusual vaginal bleeding

    *This is not a full list of side effects of Prempro, for a detailed list please contact your healthcare provider or pharmacist.

    Prempro 0.45mg/1.5mg Contraindications

    Prempro 0.45mg/1.5mg Contraindications

    There are certain contraindications or situations where the use of Prempro may not be recommended.

    1. Known or suspected pregnancy: Prempro should not be used if a woman is pregnant or suspects she may be pregnant. These medications, in menopausal doses, can not be used for birth control so there may still be a risk of pregnancy. Speak with your healthcare provider about whether you need reliable contraception.
    2. History of blood clots: Women with a history of blood clots in the legs (deep vein thrombosis) or lungs (pulmonary embolism) should avoid using Prempro. The medication can increase the risk of blood clot formation, which can be life-threatening.
    3. History of heart attack or stroke: Women with a history of heart attack or stroke should generally avoid using Prempro. The medication can increase the risk of cardiovascular events in individuals with a history of these conditions.
    4. Liver disease: Severe liver disease or liver tumors are contraindications for the use of all hormones, including conjugated estrogens and medroxyprogesterone. This medication is metabolized in the liver, and liver dysfunction can affect their clearance from the body and increase the risk of adverse effects.
    5. Uncontrolled high blood pressure: Women with uncontrolled high blood pressure should be cautious when using Prempro since it can increase blood pressure. Individuals with pre-existing hypertension may experience further elevation of blood pressure.
    6. Breast cancer or other hormone-sensitive cancers: Women with a history of breast cancer or other hormone-sensitive cancers should generally avoid using hormones containing medications. They can potentially stimulate the growth of hormone-sensitive tumors.

    It is important to note that these are general contraindications, and individual patient factors and medical history should be considered when determining the appropriateness of using Premphase. It is always recommended to consult with a healthcare professional for personalized advice.

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    What is Prempro 0.45mg/1.5mg?

    Prempro 0.45mg/1.5mg is a medication that combines two hormones, estrogen (conjugated estrogens) and progestin (medroxyprogesterone), which are used to treat symptoms of menopause in women who still have their uterus.

    Conjugated estrogens is a blend of estrogens that function as a substitute for the estrogen lost during menopause. It alleviates hot flashes, relieves vaginal dryness, and promotes bone strength.

    Medroxyprogesterone is a progestin that safeguards the uterus and aids in the prevention of uterine cancer.



    Frequently Asked Questions

    Prempro is a combination medication that contains estrogen and progestin hormones. It is primarily used to relieve menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. It can also help prevent osteoporosis in postmenopausal women.



    Whether Prempro is a good hormone replacement option depends on individual circumstances and medical history. It is important to consult with a healthcare provider to determine the most suitable hormone replacement therapy for your specific needs.

    While both medications contain a combination of estrogen and progestin hormones, their main difference is that they have different dosing schedules. Premphase is a sequential therapy that consists of two different tablets with varying hormone levels, while Prempro is a continuous therapy with a fixed combination of hormones in each tablet. Additionally, the specific hormone dosages may also differ between the two medications. 



    There are no research studies that show Prempro as a cause of weight gain. However, some women might experience water retention when using Prempro. Other factors such as lifestyle, diet, ensuring adequate intake of minerals, vitamins and nutrients in your diet or supplement program, and exercise can also contribute to weight changes. If you are concerned about your weight, talk with a doctor to review your treatment plan. 

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